Cefquinome, a 4th generation cephalosporin, is the active component in Cobactan.
The shape of the cefquinome molecule facilitates a fast distribution in the treated animals and ensures a quick passage through bacterial cell walls, resulting in a rapid bactericidal effect following injection. Cefquinome has a broad-spectrum of activity, including Gram positive and Gram negative bacteria, such as Pasteurella spp., Salmonella spp., E. coli, Staphylococcus spp., Clostridium spp., Haemophilus somnus, Actinobacillus spp. and Erysipelothrix rhusiopathiae. Cefquinome is highly resistant against inactivation by -lactamase producing bacteria.

The structure of cefquinome