Zuprevo

Zuprevo contains Tildipirosin, a 16-membered macrolide. Tildipirosin acts by inhibiting protein synthesis. It binds with the 23S ribosomal ribonucleic acid of the 50S ribosomal subunit. It is bacteriostatic or bactericidal depending on the bacterial species, individual strain and drug concentrations.

Product Description

Composition

Active
40 mg Tildipirosin/ml

Excipients
Citric acid monohydrate
Propylene glycol
Water for injections

Indications for use

Treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica and Haemophilus parasuis sensitive to tildipirosin.

Dosage/ Administration

• Intramuscular use.
• Administer 4 mg tildipirosin/kg body weight (equivalent to 1ml/10 kg body weight) once only.
• The injection volume should not exceed 5ml per injection site.
• The rubber stopper of the vial may be safely punctured up to 20 times. Otherwise, the use of a multiple-dose syringe is recommended.
• To ensure correct dosage, body weight should be determined as accurately as possible to avoid under-dosing.
• It is recommended to treat animals in the early stages of the disease and to evaluate the response to treatment within 48 hours after injection. If clinical signs of respiratory disease persist or increase, or if relapse occurs, treatment should be changed using another antibiotic, and continued until clinical signs have resolved.

Contraindications

• Do not use in case of hypersensitivity to macrolide antibiotics or to any of the excipients.
• Do not administer intravenously.

Withdrawal Period

Meat and offal:
9 days

Presentations

Box containing 1 vial of 20 ml, 50 ml, 100 ml or 250 ml.
Not all pack sizes may be marketed.

Our family of registered products differs from country to country. Please contact your local MSD/Merck Animal Health contact person for country specific product registrations and product availability.