Porcilis PRRS
Description and Vaccination Program
Vaccine against Porcine Reproductive and Respiratory Syndrome
Active ingredients
Strain DV of PRRSV
Description
Porcilis PRRS is a vaccine based on the European strain
DV of PRRS virus. Intramuscular injection or intra-dermal administration of the attenuated
live PRRSV strain DV results in active immunisation against infection with PRRS virus.
This activity is enhanced by the adjuvant Diluvac Forte.
Composition
Each dose of 2 ml (intramuscular application) or 0.2 ml (intradermal application) contains at
least 4.0 log10 TCID50 of PRRS virus strain DV. The active component is
dissolved in Diluvac Forte.
Formulation
Live freeze-dried vaccine for reconstitution with the solvent Diluvac Forte.
Indications
For active immunisation of clinically healthy pigs in a PRRS virus contaminated environment, to
reduce viraemia caused by infection with European strains of PRRS virus.
Specific claims:
For fattening pigs, the respiratory tropism is relevant. A significant improvement of rearing results
(reduced morbidity due to PRRS infection, and a better daily growth and feed conversion) until the end
of the fattening period was observed in vaccinated pigs during field trials.
For breeding pigs, the reproductive tropism is relevant. A significant improvement of the
reproductive performance in PRRS virus contaminated environments and a reduction of transplacental
virus transmission after challenge was observed in vaccinated pigs.
The interest of vaccination with Porcilis PRRS lies in obtaining a homogeneous and high immune status
against PRRS virus in a herd.
Vaccination programs
A single dose is given to pigs from weeks of age onwards. Pigs should be vaccinated at least 2-4 weeks before
a PRRS virus infection occurs. It is advised to vaccinate all target pigs within a herd from the earliest
recommended age onward.
Fattening pigs:
A single vaccination is sufficient for protection until slaughter.
Breeding pigs:
For gilts a (re)vaccination 2-4 weeks before mating is recommended.
To maintain a high a homologeous level of immunity, revaccination at regular intervals is
recommended, either before each next gestation or at random at 4 month intervals.
Pregnant sows should only be vaccinated after previous exposure to European PRRS virus.
Newly introduced PRRS virus-naïve animals (e.g. replacement gilts from PRRS virus-negative herds)
should be vaccinated prior to pregnancy.
Method of administration
2 ml by the intramuscular route or 0.2 ml by the intradermal route.
Withholding period
None
Presentation
Vials of freeze-dried vaccine containing 10, 25, 50 or 100 doses.
Storage
Store at a temperature of 2-8°C. Protect from light.
The adjuvant Diluvac Forte should be stored below 25°C.
Contra-indications
Do not use the vaccine in herds where the prevelance of European PRRS virus has not been established through reliable
diagnostic methods.
Precautions
- Vaccinate healthy pigs only
- Allow the vaccine to reach room temperature (15-25°C) before use
- Shake the vaccine before and during use
- Use sterile syringes and needles
- Vaccine should be used within 3 hours of reconstitution.